Protein HLA-C map

Identifiers
HUGO:HLA-C

References
CASCADE:KIR2DL3
CASCADE:KIR2DL2
CASCADE:KIR2DL1
 NATURAL_KILLER  map
CASCADE:KIR2DS4
PMID:11513144
KIRs constitute a family of slightly polymorphic receptors with distinct MHC-I-binding profiles for classical HLA-A, HLA-B, and HLA-C molecules. Most KIRs with two Ig domains (KIR2DL) recognize subsets of the HLA-C allotypes.

Modifications:
In compartment: TUMOR_CELL_AS_INDUCTOR_Membrane
  1. HLA-C@TUMOR_CELL_AS_INDUCTOR_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. HLA-C:​KIR2DL2@INNATE_IMMUNE_CELL_Membrane map
  2. HLA-C:​KIR2DS4@INNATE_IMMUNE_CELL_Membrane map
  3. HLA-C:​KIR2DL1|​pho@INNATE_IMMUNE_CELL_Membrane map
  4. HLA-C:​KIR2DL3|​pho@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. HLA-C@TUMOR_CELL_AS_INDUCTOR_Membrane map + KIR2DS4@INNATE_IMMUNE_CELL_Membrane map → map HLA-C:​KIR2DS4@INNATE_IMMUNE_CELL_Membrane map
  2. HLA-C@TUMOR_CELL_AS_INDUCTOR_Membrane map + KIR2DL2@INNATE_IMMUNE_CELL_Membrane map → map HLA-C:​KIR2DL2@INNATE_IMMUNE_CELL_Membrane map
  3. HLA-C@TUMOR_CELL_AS_INDUCTOR_Membrane map + KIR2DL1@INNATE_IMMUNE_CELL_Membrane map → map HLA-C:​KIR2DL1|​pho@INNATE_IMMUNE_CELL_Membrane map
  4. HLA-C@TUMOR_CELL_AS_INDUCTOR_Membrane map + KIR2DL3@INNATE_IMMUNE_CELL_Membrane map → map HLA-C:​KIR2DL3|​pho@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. IFNG@INNATE_IMMUNE_CELL_Cytosol map → map IFNG@default map
  2. ERK1/2*@INNATE_IMMUNE_CELL_Cytosol map → map ERK1/2*|​pho@INNATE_IMMUNE_CELL_Cytosol map
  3. GRB2@INNATE_IMMUNE_CELL_Cytosol map + DAP10:​NKG2D*@INNATE_IMMUNE_CELL_Membrane map → map DAP10|​pho:​GRB2:​NKG2D*@INNATE_IMMUNE_CELL_Membrane map
  4. Ca2+@Endoplasmic Reticulum map → map Ca2+@INNATE_IMMUNE_CELL_Cytosol map
  5. 2B4*|​pho:​CD48:​SH2D1A@INNATE_IMMUNE_CELL_Membrane map + 3BP2*|​pho@INNATE_IMMUNE_CELL_Membrane map → map 2B4*|​pho:​3BP2*|​pho:​CD48:​SH2D1A@INNATE_IMMUNE_CELL_Membrane map
  6. PTPN6@INNATE_IMMUNE_CELL_Cytosol map → map PTPN6@INNATE_IMMUNE_CELL_Cytosol map
  7. PTPN11@INNATE_IMMUNE_CELL_Cytosol map → map PTPN11@INNATE_IMMUNE_CELL_Cytosol map
  8. ABL1@INNATE_IMMUNE_CELL_Cytosol map → map ABL1@INNATE_IMMUNE_CELL_Cytosol map
  9. WASP*|​pho:​WIPF1@INNATE_IMMUNE_CELL_Cytosol map → map WASP*|​pho:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map