Identifiers
c-abl oncogene 1, non-receptor tyrosine kinase
ABL, "c-abl oncogene 1, receptor tyrosine kinase", "v-abl Abelson murine leukemia viral oncogene homolog 1"
HUGO:ABL1 HGNC:76 ENTREZ:25 UNIPROT:P00519
ABL proto-oncongene 1, non receptor tyrosine-kinase
HUGO:ABL1
c-abl oncogene 1, receptor tyrosine kinase
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
EMT Senescence / CELL_MATRIX_ADHESIONS
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
Cell Cycle DNA Repair / S_PHASE_CHECKPOINT
Cell Cycle DNA Repair / G2_M_CHECKPOINT
HMC:RESISTING_CELL_DEATH
Regulated Cell Death / APOPTOSIS
Regulated Cell Death / CASPASES
HMC:TUMOR_PROMOTING_INFLAMMATION
Innate Immunity / IMMUNOSUPPPRESSIVE_CORE_PATHWAYS
References
PMID:10837221
PMID:15459660, PMID:21435002, PMID:21199784, PMID:21051857
CASCADE:KIR2DL1
CASCADE:NKG2A
NATURAL_KILLER
PMID:18835194
Association of CrkII with ALBL1(c-Abl) occurred during inhibition. ABL1 phosphorylates CRK and inhibits CRK activity downstream of KIR2DL1 and NKG2A/CD94 pathway..