Protein ABL1 map

Identifiers
c-abl oncogene 1, non-receptor tyrosine kinase
ABL, "c-abl oncogene 1, receptor tyrosine kinase", "v-abl Abelson murine leukemia viral oncogene homolog 1"
HUGO:ABL1 HGNC:76 ENTREZ:25 UNIPROT:P00519
ABL proto-oncongene 1, non receptor tyrosine-kinase
HUGO:ABL1
c-abl oncogene 1, receptor tyrosine kinase

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_MATRIX_ADHESIONS  map
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
 Cell Cycle DNA Repair  map  / S_PHASE_CHECKPOINT  map
 Cell Cycle DNA Repair  map  / G2_M_CHECKPOINT  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPPRESSIVE_CORE_PATHWAYS  map

References
PMID:10837221
PMID:15459660, PMID:21435002, PMID:21199784, PMID:21051857
CASCADE:KIR2DL1
CASCADE:NKG2A
 NATURAL_KILLER  map
PMID:18835194
Association of CrkII with ALBL1(c-Abl) occurred during inhibition. ABL1 phosphorylates CRK and inhibits CRK activity downstream of KIR2DL1 and NKG2A/CD94 pathway..


Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. ABL1@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. ABL1@INNATE_IMMUNE_CELL_Cytosol map map ABL1@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. (BCAR1|​pho:​CBL|​pho:​CRK:​CRKL:​RAPGEF1)|​active@INNATE_IMMUNE_CELL_Cytosol map map BCAR1|​pho:​CBL|​pho:​CRKL|​pho:​CRK|​pho:​RAPGEF1@INNATE_IMMUNE_CELL_Cytosol map