Complex WASP*:WIPF1
Complex composition:
- WIPF1
- WASP*
WASP*|pho:WIPF1|pho@INNATE_IMMUNE_CELL_Cytosol
Identifiers
NAME:WASP*:WIPF1
References
CASCADE:KIR2DL1
PMID:16606694
Protein kinase C-theta mediates phosphorylation of WIPF1 downstream of NK activation. Inhibitory signaling from KIR2DL1 receptor.
Phosphorylated WIPF1 provides recruitment of of F-actin and MYH9 (myosin IIA) to multiprotein WASP??:WIPF1 complexs.
PMID:17890224
in macrophages WASP and WASP-interacting protein (WIP) form a complex at the phagocytic cup and that the WASP.WIP complex plays a critical role in the phagocytic cup formation.
WASP*|pho:WIPF1@INNATE_IMMUNE_CELL_Cytosol
Identifiers
NAME:WASP*:WIPF1
References
NATURAL_KILLER
CASCADE:KIR2DL1
PMID:16606694
WIPF1 forms complex with WASP. Protein kinase C-theta mediates phosphorylation of WIPF1 downstream of NK activation. Inhibitory signaling from KIR2DL1 receptor
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- WASP*|pho:WIPF1@INNATE_IMMUNE_CELL_Cytosol
- WASP*|pho:WIPF1|pho@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- ELC_MYOSIN_II*:MYH9|hm2:RLC_MYOSIN_II*|pho@INNATE_IMMUNE_CELL_Cytosol
+ WASP*|pho:WIPF1|pho@INNATE_IMMUNE_CELL_Cytosol
→
ELC_MYOSIN_II*:MYH9|hm2:RLC_MYOSIN_II*|pho:WASP*:WIPF1|pho@INNATE_IMMUNE_CELL_Cytosol
- WASP*|pho:WIPF1@INNATE_IMMUNE_CELL_Cytosol
→
WASP*|pho:WIPF1|pho@INNATE_IMMUNE_CELL_Cytosol
- WASP*|pho|active@INNATE_IMMUNE_CELL_Cytosol
+ WIPF1@INNATE_IMMUNE_CELL_Cytosol
→
WASP*|pho:WIPF1@INNATE_IMMUNE_CELL_Cytosol
As Catalyser: