Complex ELC_MYOSIN_II*:MYH9:RLC_MYOSIN_II*:WASP*:WIPF1 map
Complex composition:

  1. WASP* map
  2. WIPF1 map
  3. MYH9 map
  4. RLC_MYOSIN_II* map
  5. ELC_MYOSIN_II* map

ELC_MYOSIN_II*:​MYH9|​hm2:​RLC_MYOSIN_II*|​pho:​WASP*:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol

Identifiers
NAME:ELC_MYOSIN_II*:MYH9:RLC_MYOSIN_II*:WASP*:WIPF1

References
 MACROPHAGE  map
PMID:16606694
Protein kinase C-theta mediates phosphorylation of WIPF1 downstream of NK activation. Inhibitory signaling from KIR2DL1 receptor.
Phosphorylated WIPF1 provides recruitment of of F-actin and MYH9 (myosin IIA) to multiprotein WASP??:WIPF1 complexs.
PMID:17890224
in macrophages WASP and WASP-interacting protein (WIP) form a complex at the phagocytic cup and that the WASP.WIP complex plays a critical role in the phagocytic cup formation.

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. ELC_MYOSIN_II*:​MYH9|​hm2:​RLC_MYOSIN_II*|​pho:​WASP*:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. ELC_MYOSIN_II*:​MYH9|​hm2:​RLC_MYOSIN_II*|​pho@INNATE_IMMUNE_CELL_Cytosol map + WASP*|​pho:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map → map ELC_MYOSIN_II*:​MYH9|​hm2:​RLC_MYOSIN_II*|​pho:​WASP*:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. Actin cytoskeletal*@INNATE_IMMUNE_CELL_Cytosol map → map Actin cytoskeletal*|​hm2|​active@INNATE_IMMUNE_CELL_Cytosol map