Complex HLA-C:KIR2DS4 map
Complex composition:

  1. HLA-C map
  2. KIR2DS4 map

HLA-C:​KIR2DS4@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:HLA-C:KIR2DS4

References
 NATURAL_KILLER  map
CASCADE:KIR2DS4
in_re177( Innate Immunity  map ):
PMID:12740575, PMID:15972651
In NK cells NKG2D signaling inducese PLCG2 phosphorylation and Ca2+ release. ??The calcium signal generated by PLCG??is required for NKG2D-initiated killing.

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. HLA-C:​KIR2DS4@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. HLA-C@TUMOR_CELL_AS_INDUCTOR_Membrane map + KIR2DS4@INNATE_IMMUNE_CELL_Membrane map → map HLA-C:​KIR2DS4@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. ERK1/2*@INNATE_IMMUNE_CELL_Cytosol map → map ERK1/2*|​pho@INNATE_IMMUNE_CELL_Cytosol map
  2. Ca2+@Endoplasmic Reticulum map → map Ca2+@INNATE_IMMUNE_CELL_Cytosol map