Protein IL2RB map

Identifiers
HUGO:IL2RB

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS  map

References
 NATURAL_KILLER  map
 DENDRITIC_CELL  map
CASCADE:IL15
CASCADE:IL2
PMID:16212621
IL-2- and IL-15-induced phosphorylation of the IL-2RB chain in T cells.
PMID:10820393, PMID:24829413
IL2 receptor is expressed in dendritic cells. The IL-2R is composed of three different subunits,
IL-2R alpha (CD25), IL-2/15R beta (CD122) and gamma (CD131)

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. IL2RB@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. IL2RA:​IL2RB:​IL2RG@INNATE_IMMUNE_CELL_Membrane map
  2. IL15RA:​IL2RB:​IL2RG@INNATE_IMMUNE_CELL_Membrane map
  3. IL2:​IL2RA:​IL2RB:​IL2RG:​JAK1:​JAK3@INNATE_IMMUNE_CELL_Membrane map
  4. IL15:​IL15RA:​IL2RB|​pho:​IL2RG:​JAK1:​JAK3@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. rIL2RB@INNATE_IMMUNE_CELL_Cytosol map → map IL2RB@INNATE_IMMUNE_CELL_Cytosol map
  2. IL15RA:​IL2RB:​IL2RG@INNATE_IMMUNE_CELL_Membrane map + IL15@default map + JAK1@INNATE_IMMUNE_CELL_Cytosol map + JAK3@INNATE_IMMUNE_CELL_Cytosol map → map IL15:​IL15RA:​IL2RB|​pho:​IL2RG:​JAK1:​JAK3@INNATE_IMMUNE_CELL_Membrane map
  3. IL2RG@INNATE_IMMUNE_CELL_Membrane map + IL15RA@INNATE_IMMUNE_CELL_Membrane map + IL2RB@INNATE_IMMUNE_CELL_Cytosol map → map IL15RA:​IL2RB:​IL2RG@INNATE_IMMUNE_CELL_Membrane map
  4. IL2RG@INNATE_IMMUNE_CELL_Membrane map + IL2RA@INNATE_IMMUNE_CELL_Cytosol map + IL2RB@INNATE_IMMUNE_CELL_Cytosol map → map IL2RA:​IL2RB:​IL2RG@INNATE_IMMUNE_CELL_Membrane map
  5. IL2@default map + IL2RA:​IL2RB:​IL2RG@INNATE_IMMUNE_CELL_Membrane map + JAK1@INNATE_IMMUNE_CELL_Cytosol map + JAK3@INNATE_IMMUNE_CELL_Cytosol map → map IL2:​IL2RA:​IL2RB:​IL2RG:​JAK1:​JAK3@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. STAT1@INNATE_IMMUNE_CELL_Cytosol map → map STAT1|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
  2. gMICA@INNATE_IMMUNE_CELL_Cytosol map → map rMICA@INNATE_IMMUNE_CELL_Cytosol map
  3. gMICB@INNATE_IMMUNE_CELL_Cytosol map → map rMICB@INNATE_IMMUNE_CELL_Cytosol map
  4. STAT3@INNATE_IMMUNE_CELL_Cytosol map → map STAT3|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
  5. STAT5*@INNATE_IMMUNE_CELL_Cytosol map → map STAT5*|​pho@INNATE_IMMUNE_CELL_Cytosol map
  6. STAT4@INNATE_IMMUNE_CELL_Cytosol map → map STAT4|​pho@INNATE_IMMUNE_CELL_Cytosol map