Complex IL2:IL2RA:IL2RB:IL2RG:JAK1:JAK3 map
Complex composition:

  1. IL2RA map
  2. IL2RB map
  3. IL2RG map
  4. JAK1 map
  5. IL2 map
  6. JAK3 map

IL2:​IL2RA:​IL2RB:​IL2RG:​JAK1:​JAK3@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:IL2:IL2RA:IL2RB:IL2RG:JAK1:JAK3

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS  map

References
 NATURAL_KILLER  map
 DENDRITIC_CELL  map
CASCADE:IL2
PMID:10820393, PMID:24829413
IL2 receptor is expressed in dendritic cells. The IL-2R is composed of three different subunits,
IL-2R alpha (CD25), IL-2/15R beta (CD122) and gamma (CD131)
PMID:12095053, PMID:8683106
IL2 receptor in DC acts probably via JAK1 and JAK3 (demonstrated for NK and T-cells only)

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. IL2:​IL2RA:​IL2RB:​IL2RG:​JAK1:​JAK3@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. IL2@default map + IL2RA:​IL2RB:​IL2RG@INNATE_IMMUNE_CELL_Membrane map + JAK1@INNATE_IMMUNE_CELL_Cytosol map + JAK3@INNATE_IMMUNE_CELL_Cytosol map → map IL2:​IL2RA:​IL2RB:​IL2RG:​JAK1:​JAK3@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. STAT5*@INNATE_IMMUNE_CELL_Cytosol map → map STAT5*|​pho@INNATE_IMMUNE_CELL_Cytosol map