RNA MICA
Identifiers
HUGO:MICA
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ IMMUNOSTIMULATORY_CYTOKINE_EXPRESSION
References
NATURAL_KILLER
DENDRITIC_CELL
CASCADE:IL15
CASCADE:IFNAB
PMID:25277195
Inhibition of MIR20A or MIR93 upregulates translation of their predicted targets (MICA, MICB, ULBP2 or ULBP3) in tumor cells and upregulates NK cytotoxicity against these cells.
Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- rMICA@INNATE_IMMUNE_CELL_Cytosol
In compartment: TUMOR_CELL_AS_INDUCTOR
- rMICA@TUMOR_CELL_AS_INDUCTOR
Participates in complexes:
Participates in reactions:
As Reactant or Product:- gMICA@TUMOR_CELL_AS_INDUCTOR
→
rMICA@TUMOR_CELL_AS_INDUCTOR
- rMICA@TUMOR_CELL_AS_INDUCTOR
→
MICA@TUMOR_CELL_AS_INDUCTOR
- gMICA@INNATE_IMMUNE_CELL_Cytosol
→
rMICA@INNATE_IMMUNE_CELL_Cytosol
- rMICA@INNATE_IMMUNE_CELL_Cytosol
→
MICA@INNATE_IMMUNE_CELL_Cytosol
As Catalyser: