Gene MICA map

Identifiers
HUGO:MICA

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_EXPRESSION  map

References
 NATURAL_KILLER  map
 DENDRITIC_CELL  map
CASCADE:IL15
CASCADE:IFNAB
PMID:25277195
Hypoxia down-regulates level of MICA, MICB, ULBP2 and ULBP3 transcripts in tumor
PMID:14607946
Additionally DCs activate resting NK cells by expressing MHC class I-related chain A and B (MICA/B), ligands for NKG2D, in response to IFN-alpha and IL15 via FN-alpha/betaR or -IL-15Ralpha, respectively

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. gMICA@INNATE_IMMUNE_CELL_Cytosol map
In compartment: TUMOR_CELL_AS_INDUCTOR
  1. gMICA@TUMOR_CELL_AS_INDUCTOR map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gMICA@TUMOR_CELL_AS_INDUCTOR map → map rMICA@TUMOR_CELL_AS_INDUCTOR map
    2. gMICA@INNATE_IMMUNE_CELL_Cytosol map → map rMICA@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: