1. IL2RG
2. IL2RB
3. IL15RA
4. JAK1
5. IL15
6. JAK3

Identifiers
NAME:IL15:IL15RA:IL2RB:IL2RG:JAK1:JAK3

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity   / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS 

References
 NATURAL_KILLER 
 DENDRITIC_CELL 
CASCADE:IL15
PMID:16815076
IL-15 receptor complex contains IL15RA, IL2RG, IL2RB subunits.
IL-15-mediated signaling results in the activation of Janus kinase (JAK),
The IL-2RB chain recruits JAK1, whereas IL-2RG activates JAK3, , which in turn results in the phosphorylation and activation of STAT3 and STAT5, respectively.
in_re707( Innate Immunity  ):
PMID:12811837
TLR signaling can induces STAT1 phosphorylation via p38 and potentiate IFNG signaling.
PMID:19833085
STAT1 is activated downstream of IFNG by phosphorylation of tyrosine 701, translocates to the nucleus, binds to a regulatory DNA element termed gamma-activated sequence (GAS) and stimulates transcription of STAT1 target genes.

1. IL15:​IL15RA:​IL2RB|​pho:​IL2RG:​JAK1:​JAK3@INNATE_IMMUNE_CELL_Membrane

1. IL15RA:​IL2RB:​IL2RG@INNATE_IMMUNE_CELL_Membrane + IL15@default + JAK1@INNATE_IMMUNE_CELL_Cytosol + JAK3@INNATE_IMMUNE_CELL_Cytosol → IL15:​IL15RA:​IL2RB|​pho:​IL2RG:​JAK1:​JAK3@INNATE_IMMUNE_CELL_Membrane

1. STAT1@INNATE_IMMUNE_CELL_Cytosol → STAT1|​pho|​active@INNATE_IMMUNE_CELL_Cytosol
2. gMICA@INNATE_IMMUNE_CELL_Cytosol → rMICA@INNATE_IMMUNE_CELL_Cytosol
3. gMICB@INNATE_IMMUNE_CELL_Cytosol → rMICB@INNATE_IMMUNE_CELL_Cytosol
4. STAT3@INNATE_IMMUNE_CELL_Cytosol → STAT3|​pho|​active@INNATE_IMMUNE_CELL_Cytosol
5. STAT5*@INNATE_IMMUNE_CELL_Cytosol → STAT5*|​pho@INNATE_IMMUNE_CELL_Cytosol
6. STAT4@INNATE_IMMUNE_CELL_Cytosol → STAT4|​pho@INNATE_IMMUNE_CELL_Cytosol