Protein ITGA4 map

Identifiers
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
CD49D
HUGO:ITGA4 HGNC:6140 ENTREZ:3676 UNIPROT:P13612
HUGO:ITGA4

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_MATRIX_ADHESIONS  map
 EMT Senescence  map  / ECM  map
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / INTEGRINS  map

References
 NATURAL_KILLER  map
CASCADE:INTEGRIN_A4B1
PMID:12626562, PMID:19454690
VCAM1 is a ligand for alpha-4/beta-1 integrin cells. NKG2D ligation leads to increased adhesion NK cells to VCAM1 and ICAM1 and recruitment of integrins to the cytotoxic synapse.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. ITGA4@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. (ITGA4:​ITGB1)|​active@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. (ITGA4:​ITGB1)|​active@INNATE_IMMUNE_CELL_Membrane map → map (ITGA4:​ITGB1)|​active@INNATE_IMMUNE_CELL_Membrane map
  2. ITGB1@INNATE_IMMUNE_CELL_Membrane map + ITGA4@INNATE_IMMUNE_CELL_Membrane map → map (ITGA4:​ITGB1)|​active@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. ZAP70@INNATE_IMMUNE_CELL_Cytosol map → map ZAP70|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
  2. FYN@INNATE_IMMUNE_CELL_Cytosol map → map FYN|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
  3. PTK2B@INNATE_IMMUNE_CELL_Cytosol map → map PTK2B|​pho@INNATE_IMMUNE_CELL_Cytosol map
  4. PLD*@INNATE_IMMUNE_CELL_Cytosol map → map PLD*@INNATE_IMMUNE_CELL_Cytosol map
  5. PLA2G2A@INNATE_IMMUNE_CELL_Cytosol map → map PLA2G2A|​pho@INNATE_IMMUNE_CELL_Cytosol map
  6. PTK2@INNATE_IMMUNE_CELL_Cytosol map → map PTK2@INNATE_IMMUNE_CELL_Cytosol map
  7. LYN@INNATE_IMMUNE_CELL_Cytosol map → map LYN|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map