Complex DAG:PRKCQ
Complex composition:
- PRKCQ
- DAG
DAG:PRKCQ@INNATE_IMMUNE_CELL_Cytosol
Identifiers
NAME:DAG:PRKCQ
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ IMMUNOSTIMULATORY_CORE_PATHWAYS
References
CASCADE:IFNAB
NATURAL_KILLER
DAG:PRKCQ|pho@INNATE_IMMUNE_CELL_Cytosol
Identifiers
NAME:DAG:PRKCQ
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ IMMUNOSTIMULATORY_CORE_PATHWAYS
References
NATURAL_KILLER
in_re707( Innate Immunity
):
PMID:12811837
TLR signaling can induces STAT1 phosphorylation via p38 and potentiate IFNG signaling.
PMID:19833085
STAT1 is activated downstream of IFNG by phosphorylation of tyrosine 701, translocates to the nucleus, binds to a regulatory DNA element termed gamma-activated sequence (GAS) and stimulates transcription of STAT1 target genes.
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- DAG:PRKCQ@INNATE_IMMUNE_CELL_Cytosol
- DAG:PRKCQ|pho@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- DAG@INNATE_IMMUNE_CELL_Cytosol
+ PRKCQ@INNATE_IMMUNE_CELL_Cytosol
→
DAG:PRKCQ@INNATE_IMMUNE_CELL_Cytosol
- DAG:PRKCQ@INNATE_IMMUNE_CELL_Cytosol
→
DAG:PRKCQ|pho@INNATE_IMMUNE_CELL_Cytosol
As Catalyser:- gIRF9@INNATE_IMMUNE_CELL_Cytosol
→
rIRF9@INNATE_IMMUNE_CELL_Cytosol
- NFAT*|pho@INNATE_IMMUNE_CELL_Cytosol
→
NFAT*@INNATE_IMMUNE_CELL_Cytosol
- STAT1@INNATE_IMMUNE_CELL_Cytosol
→
STAT1|pho|active@INNATE_IMMUNE_CELL_Cytosol
- WASP*|pho:WIPF1@INNATE_IMMUNE_CELL_Cytosol
→
WASP*|pho:WIPF1|pho@INNATE_IMMUNE_CELL_Cytosol
- rGZMB@INNATE_IMMUNE_CELL_Cytosol
→
GZMB@SECRETORY_GRANULE
- rGZMA@INNATE_IMMUNE_CELL_Cytosol
→
GZMA@SECRETORY_GRANULE