Protein TLR4 map

Identifiers
HUGO:TLR4

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS  map

References
PMID:11964313, PMID:11672593, PMID:12032143, PMID:12811837.
INFG upregulates mRNA level and surface expression of TLR4 and TLR2.

TLR4@INNATE_IMMUNE_CELL_Membrane

References
in_re704( Innate Immunity  map ):
PMID:12803886
MIF upregulates membrane expression of TLR4
PMID:16267105
Exposure of macrofages to HMGB1 resulted in rapid decreases in protein level of both TLR2 and TLR4??receptors.
PMID:11672593
CSF1 up-regulates both TLR2 and TLR4 surface expression

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. TLR4@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. TICAM1:​TLR4@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. TLR4@INNATE_IMMUNE_CELL_Membrane map + TICAM1@INNATE_IMMUNE_CELL_Membrane map → map TICAM1:​TLR4@INNATE_IMMUNE_CELL_Membrane map
  2. TLR4@INNATE_IMMUNE_CELL_Membrane map → map TLR2/4*@INNATE_IMMUNE_CELL_Membrane map
  3. rTLR4@INNATE_IMMUNE_CELL_Cytosol map → map TLR4@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. gMIF@INNATE_IMMUNE_CELL_Cytosol map → map rMIF@INNATE_IMMUNE_CELL_Cytosol map
  2. IFNG@INNATE_IMMUNE_CELL_Cytosol map → map IFNG@default map
  3. TRAF3@INNATE_IMMUNE_CELL_Cytosol map → map TRAF3@INNATE_IMMUNE_CELL_Cytosol map