RNA TLR4 map

Identifiers
HUGO:TLR4

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS  map

References
PMID:11964313, PMID:11672593, PMID:12032143, PMID:12811837.
INFG upregulates mRNA level and surface expression of TLR4 and TLR2.
PMID:10734131, PMID:12803886, PMID:16283355
MIF upregulates expression of TLR4 in macrothages via PU.1 (SPI1) activation via PU.1 (SPI1) activation; PU.1 (SPI1) together with IRF8 relulates TLR4 expression in myeloid cells

rTLR4@INNATE_IMMUNE_CELL_Cytosol

References
in_re703( Innate Immunity  map ):
PMID:11964313, PMID:11672593, PMID:12032143, PMID:12811837.
INFG upregulates mRNA level and surface expression of TLR4 and TLR2.
in_re704( Innate Immunity  map ):
PMID:12803886
MIF upregulates membrane expression of TLR4
PMID:16267105
Exposure of macrofages to HMGB1 resulted in rapid decreases in protein level of both TLR2 and TLR4??receptors.
PMID:11672593
CSF1 up-regulates both TLR2 and TLR4 surface expression

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. rTLR4@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gTLR4@INNATE_IMMUNE_CELL_Cytosol map → map rTLR4@INNATE_IMMUNE_CELL_Cytosol map
    2. rTLR4@INNATE_IMMUNE_CELL_Cytosol map → map TLR4@INNATE_IMMUNE_CELL_Membrane map
    As Catalyser: