Gene MIF map

Identifiers
HUGO:MIF

References
 MACROPHAGE  map
 MDSC  map
CASCADE:TLR2_4
CASCADE:TNF
CASCADE:IL4
CASCADE:IL13
PMID:24006507
HIF1a induces MIF expression of macrophages after hypoxia. IL4+IL13 inhibit MIF expression via inhibition of HIF1a expression
H2O2 induces MIF expression in macrophages (http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2011.183.1_MeetingAbstracts.A2803)
PMID:8195715
TNF and INFG induce MIF secretion in macrophages, TLR4 signaling induces MIF expression.
PMID:23390297
MIF deficiency or small-molecule inhibition reduces splenic MDSC immune suppression in tumor-bearing mice

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. gMIF@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gMIF@INNATE_IMMUNE_CELL_Cytosol map → map rMIF@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: