Protein TICAM1 map

Identifiers
HUGO:TIKAM1

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS  map

References
CASCADE:TLR2_4
PMID:16917499
TIKAM1(TRIF) is an adaptor of TLR signaling, TLR signaling via ARHGEF2 (GEFH1)and RHOB regulates MHCII surface expression
PMID:20154735 , PMID:16306937
TICAM1 (TRIF)/TRAF pathway downstream of TLR4 is MYD88 independent.
PMID:17114424
Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. TICAM1@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. TICAM1:​TLR4@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. TLR4@INNATE_IMMUNE_CELL_Membrane map + TICAM1@INNATE_IMMUNE_CELL_Membrane map → map TICAM1:​TLR4@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. IFNG@INNATE_IMMUNE_CELL_Cytosol map → map IFNG@default map
  2. TRAF3@INNATE_IMMUNE_CELL_Cytosol map → map TRAF3@INNATE_IMMUNE_CELL_Cytosol map