Complex FCER1G:HLA-G:KIR2DL4 map
Complex composition:

  1. KIR2DL4 map
  2. HLA-G map
  3. FCER1G map

FCER1G:​HLA-G:​KIR2DL4|​pho@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:FCER1G:HLA-G:KIR2DL4

References
CASCADE:KIR2DL4
 NATURAL_KILLER  map
PMID:11994457, PMID:11513144, PMID:16287995
KIR2DL4 (CD158d) is a receptor for the nonclassical HLA-G.
in_re930( Innate Immunity  map ):
PMID:11875494
IL10-induced p38 phosphorylation.
PMID:20435894
SHIP inhibit MAPKp38 activation and prevent
MKNK1 phosphorylation by inhibiting the p38MAPK
pathway downstream of IL10.
PMID:10925299
IL13 induces p38 MAPK phosphorilation and activation, p38 MAPK participates in arginase activation??downstream of IL13.
PMID:23508573
HMGB1 induces activation (phosphorylation) of p38 via TLR4.
PMID:12811837, PMID:16713974
TLR signaling can induces STAT1 phosphorylation via p38 and potentiate IFNG signaling.
PMID:16713974
TLR2 activates (induces phosphorylation of) ERKs, JNKs, and p38 rapidly and transiently in control macrophages.
This activation is inhibited by IFNG signaling.
PMID:11438547, PMID:24378531
Both TNFR1 and TNFR2 signaling pathways are needed for activation of p38 MAPK.

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. FCER1G:​HLA-G:​KIR2DL4|​pho@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. KIR2DL4@INNATE_IMMUNE_CELL_Membrane map + HLA-G@TUMOR_CELL_AS_INDUCTOR_Membrane map + FCER1G@INNATE_IMMUNE_CELL_Membrane map → map FCER1G:​HLA-G:​KIR2DL4|​pho@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. IFNG@INNATE_IMMUNE_CELL_Cytosol map → map IFNG@default map
  2. CD247:​FCER1G:​NKp46*@INNATE_IMMUNE_CELL_Membrane map → map CD247:​CD247|​pho:​FCER1G:​NKp46*@INNATE_IMMUNE_CELL_Membrane map
  3. 2B4*|​pho:​CD48:​SH2D1A@INNATE_IMMUNE_CELL_Membrane map + 3BP2*|​pho@INNATE_IMMUNE_CELL_Membrane map → map 2B4*|​pho:​3BP2*|​pho:​CD48:​SH2D1A@INNATE_IMMUNE_CELL_Membrane map
  4. PTPN11@INNATE_IMMUNE_CELL_Cytosol map → map PTPN11@INNATE_IMMUNE_CELL_Cytosol map
  5. p38*@INNATE_IMMUNE_CELL_Cytosol map → map p38*|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map