Complex FN1:ITGA5:ITGB1
Complex composition:
- FN1
- ITGA5
- ITGB1
FN1:ITGA5:ITGB1@INNATE_IMMUNE_CELL_Membrane
Identifiers
NAME:FN1:ITGA5:ITGB1
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ INTEGRINS
References
NATURAL_KILLER
CASCADE:INTEGRIN_A5B1
PMID:9973479
Beta 1 integrin cross-linking inhibits CD16-induced phospholipase D and secretory phospholipase A2 activity and granule exocytosis in human NK cells.
in_re161( Innate Immunity
):
PMID:20814939, PMID:12731048
Phosphorylation of the ITAM sequence in the associated partner chains induces binding and phosphorylation of tyrosine kinases Syk and ZAP70 to the ITAM downstream of NKp30 or NKp46 or NKp44
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
- FN1:ITGA5:ITGB1@INNATE_IMMUNE_CELL_Membrane
Participates in reactions:
As Reactant or Product:- FN1@default
+ ITGA5:ITGB1@INNATE_IMMUNE_CELL_Membrane
→
FN1:ITGA5:ITGB1@INNATE_IMMUNE_CELL_Membrane
As Catalyser:- ZAP70@INNATE_IMMUNE_CELL_Cytosol
→
ZAP70|pho|active@INNATE_IMMUNE_CELL_Cytosol
- FYN@INNATE_IMMUNE_CELL_Cytosol
→
FYN|pho|active@INNATE_IMMUNE_CELL_Cytosol
- PTK2@INNATE_IMMUNE_CELL_Cytosol
→
PTK2@INNATE_IMMUNE_CELL_Cytosol