Protein NKp30* map

Identifiers
HUGO:NCR3

References
 NATURAL_KILLER  map
CASCADE:NKP30
CASCADE:TGFB
PMID:23414611
NKp30 (NCR3), NKp44 (NCR2), NKp46 (NCR1) are major activating receptors in NK cells (NCRs). The efficiency of tumour cell killing by NK cells has been shown to correlate with the expression level of the NCRs
PMID:10562324, PMID:11385609, PMID:12731048
NKp30 cooperates with NKp46 and NKp44 in the induction of NK-mediated cytotoxicity probably via the same pathways. The engagement of one NCR appears to be able to activate the signaling cascades associated with the other NCR, possibly resulting in the amplification of the activating signals.
PMID:10562324
NKp30 is involeded in the Induction of natural cytotoxicity against tumor cells.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. NKp30*@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CD247:​NKp30*@INNATE_IMMUNE_CELL_Membrane map
  2. CD247|​pho:​NKp30*@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. CD247:​NKp30*@INNATE_IMMUNE_CELL_Membrane map → map CD247|​pho:​NKp30*@INNATE_IMMUNE_CELL_Membrane map
  2. CD247@INNATE_IMMUNE_CELL_Cytosol map + NKp30*@INNATE_IMMUNE_CELL_Membrane map → map CD247:​NKp30*@INNATE_IMMUNE_CELL_Membrane map
  3. rNKp30*@INNATE_IMMUNE_CELL_Cytosol map → map NKp30*@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. SYK@INNATE_IMMUNE_CELL_Cytosol map → map SYK|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
  2. ZAP70@INNATE_IMMUNE_CELL_Cytosol map → map ZAP70|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
  3. IL2@INNATE_IMMUNE_CELL_Cytosol map → map IL2@default map