Complex FCAR:FCER1G:Immunoglobulins*
Complex composition:
- FCAR
- Immunoglobulins*
- FCER1G
FCAR:FCER1G|pho:Immunoglobulins*@INNATE_IMMUNE_CELL_Membrane
Identifiers
NAME:FCAR:FCER1G:Immunoglobulins*
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ FC_RECEPTORS
References
MACROPHAGE
CASCADE:FCAR
PMID:15081523
Fc??RI is dependent on association with the FcR?? chain for signalling and function
in_re160( Innate Immunity
):
NATURAL_KILLER
PMID:20814939, PMID:12731048
Phosphorylation of the ITAM sequence in the associated partner chains induces binding and phosphorylation of tyrosine kinases Syk and ZAP70 to the ITAM downstream of NKp30 or NKp46 or NKp44
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
- FCAR:FCER1G|pho:Immunoglobulins*@INNATE_IMMUNE_CELL_Membrane
Participates in reactions:
As Reactant or Product:- Immunoglobulins*@TUMOR_CELL_AS_INDUCTOR
+ FCAR@INNATE_IMMUNE_CELL_Membrane
+ FCER1G@INNATE_IMMUNE_CELL_Membrane
→
FCAR:FCER1G|pho:Immunoglobulins*@INNATE_IMMUNE_CELL_Membrane
As Catalyser:- TNF@INNATE_IMMUNE_CELL_Cytosol
→
TNF@default
- IL6@INNATE_IMMUNE_CELL_Cytosol
→
IL6@default
- SYK@INNATE_IMMUNE_CELL_Cytosol
→
SYK|pho|active@INNATE_IMMUNE_CELL_Cytosol