Protein DEPTOR map

Identifiers
HUGO:DEPTOR
DEP domain containing MTOR-interacting protein
HUGO:DEPTOR HGNC:22953 ENTREZ:64798 UNIPROT:Q8TB45 GENECARDS:DEPTOR KEGG:64798 ATLASONC:GC_DEPTOR WIKI:DEPTOR

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / CORE  map
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CORE_PATHWAYS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:16469695 PMID:26159692 PMID:23087689
PMID:16469695, PMID:26159692
mTOR Complex 1 (mTORC1) is composed of mTOR itself, regulatory-associated protein of mTOR (Raptor), mammalian lethal with SEC13 protein 8 (MLST8) and the recently identified PRAS40 and DEPTOR
 NATURAL_KILLER  map
 DENDRITIC_CELL  map
PMID:19446321
PMID:19706736


Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. DEPTOR:​MLST8:​ORP1L*:​PRAS40*:​RILP@INNATE_IMMUNE_CELL_Cytosol map
  2. (DEPTOR:​MLST8:​MTOR|​pho:​PRAS40*:​RPTOR)|​active@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. DEPTOR:​MLST8:​ORP1L*:​PRAS40*:​RILP@INNATE_IMMUNE_CELL_Cytosol map map (DEPTOR:​MLST8:​MTOR|​pho:​PRAS40*:​RPTOR)|​active@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. IFNG@INNATE_IMMUNE_CELL_Cytosol map map IFNG@default map
  2. GZMB@SECRETORY_GRANULE map map GZMB@default map
  3. GZMA@SECRETORY_GRANULE map map GZMA@default map
  4. gIL10@INNATE_IMMUNE_CELL_Cytosol map map rIL10@INNATE_IMMUNE_CELL_Cytosol map