Complex BCAR1:CRK:DOCK1 map
Complex composition:

  1. BCAR1 map
  2. CRK map
  3. DOCK1 map


BCAR1:​CRK:​DOCK1@INNATE_IMMUNE_CELL_Cytosol

Identifiers
NAME:BCAR1:CRK:DOCK1

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CORE_PATHWAYS  map

References
 MACROPHAGE  map
CASCADE:INTEGRIN_AVB5
PMID:14697347, PMID:??11146654
Integrin ??v??5 regulates phagocytosis via CRK /DOCK1 (DOCK180) /RAC1 pathway downstream of.
Integrin ??v??5 activation results in recruitment of the p130cas???CrkII???Dock180 complex and RAC1 activation.
in_re167( Innate Immunity  map ):
PMID:??12094222??
VAV proteins activate RAC1 via induction of GDP/GTP exchange.


Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. BCAR1:​CRK:​DOCK1@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. CRK@INNATE_IMMUNE_CELL_Cytosol map + DOCK1@INNATE_IMMUNE_CELL_Cytosol map + BCAR1@INNATE_IMMUNE_CELL_Cytosol map map BCAR1:​CRK:​DOCK1@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. GDP:​RAC1_2*@INNATE_IMMUNE_CELL_Cytosol map + GTP@INNATE_IMMUNE_CELL_Cytosol map map (GTP:​RAC1_2*)|​active@INNATE_IMMUNE_CELL_Cytosol map + GDP@INNATE_IMMUNE_CELL_Cytosol map