Complex CD11a*:CD18* map
Complex composition:

  1. CD18* map
  2. CD11a* map

CD11a*:​CD18*@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:CD11a*:CD18*

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / INTEGRINS  map

References
 NATURAL_KILLER  map
CASCADE:LFA1
CASCADE:NKG2D
PMID:15356110
ICAM1 assosiation with LAF-1 provides NK cell cytotoxicity
via polarization of perforin cytotoxic granules. This signaling is
very sensitive to inhibition of actin polymerization by cytochalasin D, of Src family tyrosine kinases by PP1, and was partially sensitive to inhibition of PI3K by wortmannin.
LFA-1-dependent cytotoxicity is sensitive to inhibition by killer cell Ig-like receptors ( CD158a and CD158b).

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CD11a*:​CD18*@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. DNAM1*|​pho@INNATE_IMMUNE_CELL_Membrane map + CD11a*:​CD18*@INNATE_IMMUNE_CELL_Membrane map → map CD11a*:​CD18*:​DNAM1*|​pho@INNATE_IMMUNE_CELL_Membrane map
  2. CD18*@INNATE_IMMUNE_CELL_Membrane map + CD11a*@INNATE_IMMUNE_CELL_Membrane map → map CD11a*:​CD18*@INNATE_IMMUNE_CELL_Membrane map
As Catalyser: