Protein GSF3 map

Identifiers
HUGO:GSF3

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS  map

References
 MDSC  map
 NEUTROPHIL  map
CASCADE:GSF3
PMID:22754783
CSF3 (G-CSF) secreted by tumors imduces MDSC signalings.
PMID:20581311
G-CSF signaling by STAT3 controls c-myc transcription by regulating the ratio of C/EBP?? to C/EBP?? at the c-myc promoter
PMID:24091328
G-CSF???induced IRF-8 downregulation via STAT3 in MDSC

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. GSF3@INNATE_IMMUNE_CELL_Cytosol map
In compartment: default
  1. GSF3@default map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CSF3R:​GSF3@INNATE_IMMUNE_CELL_Membrane map
  2. CSF3R:​GSF3:​JAK1|​pho:​JAK2|​pho@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. CSF3R:​GSF3@INNATE_IMMUNE_CELL_Membrane map + JAK1|​pho@INNATE_IMMUNE_CELL_Cytosol map + JAK2|​pho@INNATE_IMMUNE_CELL_Cytosol map → map CSF3R:​GSF3:​JAK1|​pho:​JAK2|​pho@INNATE_IMMUNE_CELL_Membrane map
  2. GSF3@INNATE_IMMUNE_CELL_Cytosol map → map GSF3@default map
  3. GSF3@INNATE_IMMUNE_CELL_Cytosol map → map IMMUNE_SUPRESSION@default map
  4. GSF3@default map + CSF3R@INNATE_IMMUNE_CELL_Membrane map → map CSF3R:​GSF3@INNATE_IMMUNE_CELL_Membrane map
  5. rCSF3@INNATE_IMMUNE_CELL_Cytosol map → map GSF3@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. JAK1@INNATE_IMMUNE_CELL_Cytosol map → map JAK1|​pho@INNATE_IMMUNE_CELL_Cytosol map
  2. JAK2@INNATE_IMMUNE_CELL_Cytosol map → map JAK2|​pho@INNATE_IMMUNE_CELL_Cytosol map
  3. STAT3@INNATE_IMMUNE_CELL_Cytosol map → map STAT3|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map