Protein CSF3R map

Identifiers
HUGO:CSF3R

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS  map

References
 MDSC  map
 NEUTROPHIL  map
CASCADE:GSF3
PMID:20237318
GSF3R is a receptor for GSF3 in myeloid cells.
The receptor for CSF3 (CSF3R) belongs to the cytokine receptor type I superfamily, which engages the canonical Janus kinase (Jak)/signal transducer and activator of transcription (STAT), Ras/Raf/MAP kinase, and PKB/Akt pathways.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CSF3R@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CSF3R:​GSF3@INNATE_IMMUNE_CELL_Membrane map
  2. CSF3R:​GSF3:​JAK1|​pho:​JAK2|​pho@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. CSF3R:​GSF3@INNATE_IMMUNE_CELL_Membrane map + JAK1|​pho@INNATE_IMMUNE_CELL_Cytosol map + JAK2|​pho@INNATE_IMMUNE_CELL_Cytosol map → map CSF3R:​GSF3:​JAK1|​pho:​JAK2|​pho@INNATE_IMMUNE_CELL_Membrane map
  2. GSF3@default map + CSF3R@INNATE_IMMUNE_CELL_Membrane map → map CSF3R:​GSF3@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. JAK1@INNATE_IMMUNE_CELL_Cytosol map → map JAK1|​pho@INNATE_IMMUNE_CELL_Cytosol map
  2. JAK2@INNATE_IMMUNE_CELL_Cytosol map → map JAK2|​pho@INNATE_IMMUNE_CELL_Cytosol map
  3. STAT3@INNATE_IMMUNE_CELL_Cytosol map → map STAT3|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map