RNA NKG2D* map

Identifiers
HUGO:KLRK1

References
 NATURAL_KILLER  map
CASCADE:TGFB
CASCADE:MIF
PMID:22491735
MiR-1245 is a direct negative regulator of NKG2D in NK cells downstream of TGFB.
Knocking down microRNA-1245 in natural killer cells resulted in higher NKG2D expression and relative resistance to the effect of TGFB1.
PMID:12646700
TGFB1 downderulates NKp30 and NKG2D mRNA and protein level.
PMID:18490733
MIF inhibits NK cell activity through a transcriptional down-regulation of NKG2D

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. rNKG2D*@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. MIR1245A:​NKG2D*@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. rNKG2D*@INNATE_IMMUNE_CELL_Cytosol map → map NKG2D*@INNATE_IMMUNE_CELL_Cytosol map
  2. gNKG2D*@INNATE_IMMUNE_CELL_Cytosol map → map rNKG2D*@INNATE_IMMUNE_CELL_Cytosol map
  3. MIR1245A:​NKG2D*@INNATE_IMMUNE_CELL_Cytosol map → map degraded
  4. arMIR1245A@INNATE_IMMUNE_CELL_Cytosol map + rNKG2D*@INNATE_IMMUNE_CELL_Cytosol map → map MIR1245A:​NKG2D*@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser: