Antisense RNA MIR1245A map

Identifiers
HUGO:MIR1245A

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / MIRNA_TF_IMMUNOSUPPRESSIVE  map

References
 NATURAL_KILLER  map
CASCADE:TGFB
PMID:22491735
TGFB1-induced miR-1245 over-expression occurs at the level of post-transcriptional processing.
Human microRNA-1245 downregulates the NKG2D receptor in NK cells and impairs NKG2D-mediated functions downstream of TGFB.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. arMIR1245A@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. MIR1245A:​NKG2D*@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. MIR1245A:​NKG2D*@INNATE_IMMUNE_CELL_Cytosol map → map degraded
  2. arMIR1245A@INNATE_IMMUNE_CELL_Cytosol map + rNKG2D*@INNATE_IMMUNE_CELL_Cytosol map → map MIR1245A:​NKG2D*@INNATE_IMMUNE_CELL_Cytosol map
  3. gMIR1245A@INNATE_IMMUNE_CELL_Cytosol map → map arMIR1245A@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser: