Identifiers
HUGO:MIR1245A
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
Innate Immunity / MIRNA_TF_IMMUNOSUPPRESSIVE
References
NATURAL_KILLER
CASCADE:TGFB
PMID:22491735
TGFB1-induced miR-1245 over-expression occurs at the level of post-transcriptional processing.
Human microRNA-1245 downregulates the NKG2D receptor in NK cells and impairs NKG2D-mediated functions downstream of TGFB.