Complex MIR1245A:NKG2D*
Complex composition:
- NKG2D*
- MIR1245A
MIR1245A:NKG2D*@INNATE_IMMUNE_CELL_Cytosol
Identifiers
NAME:MIR1245A:NKG2D*
References
NATURAL_KILLER
CASCADE:TGFB
PMID:22491735
TGFB1-induced miR-1245 over-expression occurs at the level of post-transcriptional processing.
Human microRNA-1245 downregulates the NKG2D receptor in NK cells and impairs NKG2D-mediated functions downstream of TGFB.
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- MIR1245A:NKG2D*@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- MIR1245A:NKG2D*@INNATE_IMMUNE_CELL_Cytosol
→
degraded
- arMIR1245A@INNATE_IMMUNE_CELL_Cytosol
+ rNKG2D*@INNATE_IMMUNE_CELL_Cytosol
→
MIR1245A:NKG2D*@INNATE_IMMUNE_CELL_Cytosol
As Catalyser: