Complex NFKB1_p50*:RELA:p100
Complex composition:
- RELA
- NFKB1_p50*
- p100
NFKB1_p50*:RELA:p100@INNATE_IMMUNE_CELL_Cytosol
Identifiers
NAME:NFKB1_p50*:RELA:p100
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ IMMUNOSTIMULATORY_CORE_PATHWAYS
References
PMID:17254973
NfkB heterodiners could be also bloked by p52 precursor, protein p100. Dissosiation of p100 from the comprex reactivate NF-kB signaling
NIK and IKK1 regulates the degradation of nfkb2 p100 to effect NF-??B/RelA activation.
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- NFKB1_p50*:RELA:p100@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- NFKB1_p50*:RELA:p100@INNATE_IMMUNE_CELL_Cytosol
→
NFKB1_p50*:RELA@INNATE_IMMUNE_CELL_Cytosol
+ p100@INNATE_IMMUNE_CELL_Cytosol
As Catalyser: