Complex IL6:IL6R:gp130* map
Complex composition:

  1. gp130* map
  2. IL6R map
  3. IL6 map

IL6:​IL6R:​gp130*|​Y759_pho@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:IL6:IL6R:gp130*

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS  map

References
PMID:1439146
IL6 signaling acts through IL6 receptor and receptor-associated signal transducer, gp130
9716487??
IL6 signaling acts through jak/stat pathway, probably via Jak1, Jak2 and Tyk2

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. IL6:​IL6R:​gp130*|​Y759_pho@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. IL6:​IL6R:​gp130*|​Y759_pho@INNATE_IMMUNE_CELL_Membrane map + JAK1|​pho@INNATE_IMMUNE_CELL_Cytosol map + TYK2|​pho@INNATE_IMMUNE_CELL_Cytosol map + JAK2|​pho@INNATE_IMMUNE_CELL_Cytosol map → map IL6:​IL6R:​JAK1|​pho:​JAK2|​pho:​TYK2|​pho:​gp130*|​Y759_pho@INNATE_IMMUNE_CELL_Membrane map
  2. IL6@default map + IL6R:​gp130*|​Y759_pho@INNATE_IMMUNE_CELL_Membrane map → map IL6:​IL6R:​gp130*|​Y759_pho@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. JAK1@INNATE_IMMUNE_CELL_Cytosol map → map JAK1|​pho@INNATE_IMMUNE_CELL_Cytosol map
  2. TYK2@INNATE_IMMUNE_CELL_Cytosol map → map TYK2|​pho@INNATE_IMMUNE_CELL_Cytosol map
  3. JAK2@INNATE_IMMUNE_CELL_Cytosol map → map JAK2|​pho@INNATE_IMMUNE_CELL_Cytosol map