Antisense RNA MIR125B1 map

Identifiers
microRNA 125b-1
HUGO:MIR125B1 HGNC:31506 ENTREZ:406911
HUGO:MIR125B1

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / MIRNA_TF_IMMUNOSTIMULATORY  map

References
PMID:16243976
IRF4 is a target of MIR125B1, inhibition of IRF4 by MIR125B1 ion resulted in increased surface expression of MHC II, CD40, CD86, CD80 and IFNGR

arMIR125B1@INNATE_IMMUNE_CELL_Cytosol

References
in_re692( Innate Immunity  map ):
PMID:22003200
IRF4 is a target of MIR125B1, inhibition of IRF4 by MIR125B1
resulted in increased surface expression of MHC II, CD40, CD86,
CD80 and IFNGR.
MIR125B potentiate response to IFNG, probably via
induction of IFNGR surface expression
and induces tumoricidal activity of macrophages.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. arMIR125B1@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. IRF4:​MIR125B1@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. IRF4:​MIR125B1@INNATE_IMMUNE_CELL_Cytosol map → map degraded
  2. rIRF4@INNATE_IMMUNE_CELL_Cytosol map + arMIR125B1@INNATE_IMMUNE_CELL_Cytosol map → map IRF4:​MIR125B1@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. IFNGR1@INNATE_IMMUNE_CELL_Membrane map + IFNGR2@INNATE_IMMUNE_CELL_Membrane map → map IFNGR1:​IFNGR2@INNATE_IMMUNE_CELL_Membrane map