Complex IRF4:MIR125B1
Complex composition:
- IRF4
- MIR125B1
IRF4:MIR125B1@INNATE_IMMUNE_CELL_Cytosol
Identifiers
NAME:IRF4:MIR125B1
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
Innate Immunity
/ IMMUNOSUPPPRESSIVE_CORE_PATHWAYS
Innate Immunity
/ MIRNA_TF_IMMUNOSUPPRESSIVE
References
PMID:16243976
IRF4 is a target of MIR125B1, inhibition of IRF4 by MIR125B1 ion resulted in increased surface expression of MHC II, CD40, CD86, CD80 and IFNGR
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- IRF4:MIR125B1@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- IRF4:MIR125B1@INNATE_IMMUNE_CELL_Cytosol
→
degraded
- rIRF4@INNATE_IMMUNE_CELL_Cytosol
+ arMIR125B1@INNATE_IMMUNE_CELL_Cytosol
→
IRF4:MIR125B1@INNATE_IMMUNE_CELL_Cytosol
As Catalyser: