Complex NFKB1_p50*:RELB map
Complex composition:

  1. RELB map
  2. NFKB1_p50* map

NFKB1_p50*:​RELB@INNATE_IMMUNE_CELL_Cytosol

Identifiers
NAME:NFKB1_p50*:RELB

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CORE_PATHWAYS  map

References
 DENDRITIC_CELL  map
PMID:2308644
RelB promoted DC activation not as the expected RelB-p52 effector of the noncanonical NF-??B pathway, but as a RelB-p50 dimer regulated by canonical I??Bs, I??B?? and I??B??.
TLRs activate RelB-p50 via the canonical NF??B pathway
IKKB signaling is required for RelB activation.
PMID:23394901
dimer RelB/p50 rather than the p50/p50 complex inhibits TNF production in LPS-stimulated DCs and macrophages. This implies that the non-canonical RelB/p50 could modulate the canonical p65/p50 pathway.
PMID:19655301
RelB/p50 regulates CCL19 production, but fails to promote human DC maturation

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. NFKB1_p50*:​RELB@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. NFKB1_p50*:​RELB@INNATE_IMMUNE_CELL_Cytosol map → map NFkB*@INNATE_IMMUNE_CELL_Cytosol map
  2. IL10RA:​IkB*|​pho:​NFKB1_p50*@INNATE_IMMUNE_CELL_Cytosol map → map NFKB1_p50*:​RELB@INNATE_IMMUNE_CELL_Cytosol map + IkB*|​pho@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser: