Reaction state_transition in_re477
O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol
→ O_sub_2_endsub__super_-_endsuper_@INNATE_IMMUNE_CELL_Cytosol
Reaction regulators:
- Catalysis
- ARG1@INNATE_IMMUNE_CELL_Cytosol
- CYBA:CYBB:FAD:GTP:NCF1:NCF2:NCF4:RAC1_2*:heme@INNATE_IMMUNE_CELL_Cytosol
- RAGE*:S100A8:S100A9@INNATE_IMMUNE_CELL_Membrane
- Inhibition
- TGFB*:TGFBR1:TGFBR2@INNATE_IMMUNE_CELL_Membrane
References
PMID:19732719
Inhibition of TGF-?? signaling??in vivo??increases CD11b+??cell cytotoxicity via an oxygen radical-dependent mechanism (superoxide?? and H2O2 production) in neutrophils