Simple molecule O_sub_2_endsub_ map
O_sub_2_endsub_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane

Identifiers
CHEBI:15379, KEGGCOMPOUND:C00007, CAS:7782-44-7

References
PMID:19372727
The enzyme responsible for O2???- production is called the NADPH oxidase or respiratory burst oxidase. This multicomponent enzyme system is composed of two transmembrane proteins (p22phox and gp91phox, also called NOX2, which together form the cytochrome b558) and four cytosolic proteins (p47phox, p67phox, p40phox and a GTPase Rac1 or Rac2), which assemble at membrane sites upon cell activation.

O_sub_2_endsub_@TUMOR_CELL_AS_INDUCTOR_Membrane

References
PMID:19372727
The enzyme responsible for O2???- production is called the NADPH oxidase or respiratory burst oxidase. This multicomponent enzyme system is composed of two transmembrane proteins (p22phox and gp91phox, also called NOX2, which together form the cytochrome b558) and four cytosolic proteins (p47phox, p67phox, p40phox and a GTPase Rac1 or Rac2), which assemble at membrane sites upon cell activation.

O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / NO_ROS_PRODUCTION  map

References
PMID:19372727
The enzyme responsible for O2???- production is called the NADPH oxidase or respiratory burst oxidase. This multicomponent enzyme system is composed of two transmembrane proteins (p22phox and gp91phox, also called NOX2, which together form the cytochrome b558) and four cytosolic proteins (p47phox, p67phox, p40phox and a GTPase Rac1 or Rac2), which assemble at membrane sites upon cell activation.
PMID:18809714, PMID:12645005
S100A9 regulates myeloid cell differentiation via reactive oxygen species (ROS), probabli via NAPDH oxidase.
S100A9 may suppress myeloid cell differentiation via persistent up-regulation of ROS in progenitor cells.
in_re477( Innate Immunity  map ):
PMID:19732719
Inhibition of TGF-?? signaling??in vivo??increases CD11b+??cell cytotoxicity via an oxygen radical-dependent mechanism (superoxide?? and H2O2 production) in neutrophils

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol map
In compartment: PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
  1. O_sub_2_endsub_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map
In compartment: TUMOR_CELL_AS_INDUCTOR_Membrane
  1. O_sub_2_endsub_@TUMOR_CELL_AS_INDUCTOR_Membrane map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. O_sub_2_endsub_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map → map O_sub_2_endsub__super_-_endsuper_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map
    2. O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol map → map O_sub_2_endsub__super_-_endsuper_@INNATE_IMMUNE_CELL_Cytosol map
    3. L-arginine@INNATE_IMMUNE_CELL_Cytosol map + O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol map + NADPH@INNATE_IMMUNE_CELL_Cytosol map → map NO@INNATE_IMMUNE_CELL_Cytosol map + L-citrulin@INNATE_IMMUNE_CELL_Cytosol map + NADP+@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. PtdSer@TUMOR_CELL_AS_INDUCTOR_Membrane map → map oxPS@default map