RNA TGFB1 map

Identifiers
HUGO:TGFB1

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS  map

References
PMID:16327802
IL13 and TNF inducese TGFB1 expression via AP-1 transcription factors.IL13 induces binding of c-jun and fra2 ti TGFB1 promotor, and TNF binding of c-jun, JunD and c-fos
PMID:20644162
Cytokine-induced CD33+ human MDSCs have upregulated iNOS, TGF??, VEGF.

rTGFB1@INNATE_IMMUNE_CELL_Cytosol

References
in_re1364( Innate Immunity  map ):
PMID:16327802
IL13 and TNF together (but neither IL-13 nor TNF alone) upregulates TGFB1 expression downstream of IL13RA2.
IL13 and TNF inducese TGFB1 expression via AP-1 transcription factors.IL13 induces binding of c-jun and fra2 ti TGFB1 promotor, and TNF binding of c-jun, JunD and c-fos.
PMID:21372296
HMGB1 markedly increased the expression of the genes for VEGF, and TGFB1 in
peritoneal macrophages via TLR4-dependent mechanisms.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. rTGFB1@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gTGFB1@INNATE_IMMUNE_CELL_Cytosol map → map rTGFB1@INNATE_IMMUNE_CELL_Cytosol map
    2. rTGFB1@INNATE_IMMUNE_CELL_Cytosol map → map TGFB1@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: