Protein Fc_gamma_RI* map

Identifiers
HUGO:FCGR1A HUGO:FCGR1B

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / FC_RECEPTORS  map

References
 MACROPHAGE  map
 NEUTROPHIL  map
CASCADE:Fc_gamma_RI
PMID:2139103
Fc gamma RI and Fc gamma RII on whichever cells they were expressed were capable of phagocytosing anti-Fc gamma R mAb-coated erythrocytes. Furthermore, Fc gamma RIII on mononuclear phagocytes, which appears to be a conventional integral membrane protein that spans the lipid bilayer, was capable of phagocytosing anti-Fc gamma RIII-coated erythrocytes
PMID:8064233
Hck, Lyn binds to Fc_gamma_RI (cd64) in monocytes and probably
phosphorylate ignal transducing gamma subunit of the high-affinity IgE receptor (Fc epsilon RI gamma).
Induction of cytoplasmic protein tyrosine phosphorylation by Fc gamma RI cross-linking is known to be important in mediating Fc gamma RI-coupled effector functions.
PMID:26819959
Involvement of the high-affinity receptor for IgG (Fc gamma RI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. Fc_gamma_RI*@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. FCER1G|​pho:​Fc_gamma_RI*:​Immunoglobulins*@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. Immunoglobulins*@TUMOR_CELL_AS_INDUCTOR map + Fc_gamma_RI*@INNATE_IMMUNE_CELL_Membrane map + FCER1G@INNATE_IMMUNE_CELL_Membrane map → map FCER1G|​pho:​Fc_gamma_RI*:​Immunoglobulins*@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. SYK@INNATE_IMMUNE_CELL_Cytosol map → map SYK|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map