Protein CR1 map

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / DANGER_SIGNAL_PATHWAYS  map

References
 NEUTROPHIL  map
 MACROPHAGE  map
CASCADE:CR1
PMID:11120776, PMID:2972794
CR1 is a receptor for all the primary opsonins of complement, namely, MBL, C1q, C4b, and C3b.
PMID:7584139, PMID:8326130
CR1 pathway induces phagocytosis via PLD activation and mobilization of intracellular Ca2+.

CR1@INNATE_IMMUNE_CELL_Membrane

References
in_re177( Innate Immunity  map ):
PMID:12740575, PMID:15972651
In NK cells NKG2D signaling inducese PLCG2 phosphorylation and Ca2+ release. ??The calcium signal generated by PLCG??is required for NKG2D-initiated killing.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CR1@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. CR1@INNATE_IMMUNE_CELL_Membrane map → map CR1@INNATE_IMMUNE_CELL_Membrane map
    As Catalyser:
    1. Ca2+@Endoplasmic Reticulum map → map Ca2+@INNATE_IMMUNE_CELL_Cytosol map
    2. PLD*@INNATE_IMMUNE_CELL_Cytosol map → map PLD*@INNATE_IMMUNE_CELL_Cytosol map