Protein MAF map

Identifiers
HUGO:MAF

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / MIRNA_TF_IMMUNOSUPPRESSIVE  map

References
PMID:15749884
IL-4 dose dependently stimulated c-Maf expression (both short and long forms) in resting monocytes.c-Maf binds to the ???206/???171 region in the IL-10 promoter and upregulates IL10 expression.

MAF@INNATE_IMMUNE_CELL_Cytosol

References
in_re423( Innate Immunity  map ):
PMID:20547845
TLR4 signaling downstream of HMGB1 induces secretion of IL10
PMID:16713974
RNAi-mediated knockdown of CREB, Fos, and Jun expression resulted in diminished TLR2-induced IL-10 production
GSK3B inhitits activation (DNA binding) of AP-1 factors.
JNK is a classical activator of AP1 transcription factors.
Inhibition of JNK downregulates IL10 expression. Probably via
AP1.
PMID:17404308
CSF1 upregulates expression of IL10 and CCL2 probably via CSF1R.
PMID:15749884
c-Maf binds to the ???206/???171 region in the IL-10 promoter and upregulates IL10 expression.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. MAF@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rMAF@INNATE_IMMUNE_CELL_Cytosol map → map MAF@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. gIL10@INNATE_IMMUNE_CELL_Cytosol map → map rIL10@INNATE_IMMUNE_CELL_Cytosol map