RNA DAP12* map

Identifiers
HUGO:TYROBP

References
 NATURAL_KILLER  map
CASCADE:TGFB
PMID:24586048
Suppression of NK cells is a result of TGF-?? induction of microRNA (miR)-183, which binds and represses DNAX activating protein 12 kDa (DAP12), a signal adaptor for lytic function in NK cells
and interupts DAP12 dependent signaling (at least via NKp44 and KIR2DS4 receptors) .

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. rDAP12*@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. DAP12*:​MIR183@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. gDAP12*@INNATE_IMMUNE_CELL_Cytosol map → map rDAP12*@INNATE_IMMUNE_CELL_Cytosol map
  2. rDAP12*@INNATE_IMMUNE_CELL_Cytosol map → map DAP12*@INNATE_IMMUNE_CELL_Membrane map
  3. DAP12*:​MIR183@INNATE_IMMUNE_CELL_Cytosol map → map degraded
  4. rDAP12*@INNATE_IMMUNE_CELL_Cytosol map + arMIR183@INNATE_IMMUNE_CELL_Cytosol map → map DAP12*:​MIR183@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser: