Identifiers
microRNA 20a
HUGO:MIR20A HGNC:31577 ENTREZ:406982
HUGO:MIR20A
HUGO:MIR20A HGNC:31577 ENTREZ:406982 GENECARDS:MIR20A KEGG:406982 ATLASONC:GC_MIR20A WIKI:MIR20A
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
Innate Immunity / IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS
Innate Immunity / MIRNA_TF_IMMUNOSUPPRESSIVE
HMC:EVADING_GROWTH_SUPPRESSORS
Survival / HEDGEHOG
References
NATURAL_KILLER
PMID:25277195, PMID:24813230
Inhibition of MIR20A or MIR93 upregulates translation of their predicted targets (MICA, MICB, ULBP2 or ULBP3) in tumor cells and upregulates NK cytotoxicity against these cells.
PMID:21383238
Both miR-17-5p and miR-20a alleviate suppressive potential of myeloid-derived suppressor cells and macrophages by modulating STAT3 expression.
PMID:20851997