Protein HLA-B
Identifiers
HUGO:HLA-B
References
CASCADE:KIR3DL1
NATURAL_KILLER
PMID:9605119
Ligation of the NK cell receptor KIR3DL1 by HLA-Bw4 allotypes resulted in inhibition of cytotoxicity against HLA-B*4403-transfected melanomas as well as against melanomas endogenously expressing HLA-Bw4 allotypes.
Modifications:
In compartment: TUMOR_CELL_AS_INDUCTOR_Membrane
- HLA-B@TUMOR_CELL_AS_INDUCTOR_Membrane
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
- HLA-B:KIR3DL1|pho@INNATE_IMMUNE_CELL_Membrane
Participates in reactions:
As Reactant or Product:- HLA-B@TUMOR_CELL_AS_INDUCTOR_Membrane
+ KIR3DL1@INNATE_IMMUNE_CELL_Membrane
→
HLA-B:KIR3DL1|pho@INNATE_IMMUNE_CELL_Membrane
As Catalyser:- PTPN6@INNATE_IMMUNE_CELL_Cytosol
→
PTPN6@INNATE_IMMUNE_CELL_Cytosol
- PTPN11@INNATE_IMMUNE_CELL_Cytosol
→
PTPN11@INNATE_IMMUNE_CELL_Cytosol