Reaction state_transition in_re181 map

PLCG1@INNATE_IMMUNE_CELL_Cytosol map → PLCG1|​pho@INNATE_IMMUNE_CELL_Cytosol map

Reaction regulators:
Catalysis
  1. IFNA*@default map
  2. GRB2:​LAT|​pho@INNATE_IMMUNE_CELL_Cytosol map
  3. SH2D1B|​pho:​SLAMF7|​pho|​hm2@INNATE_IMMUNE_CELL_Membrane map
  4. 2B4*|​pho:​3BP2*|​pho:​CD48:​SH2D1A@INNATE_IMMUNE_CELL_Membrane map
  5. LAT|​pho@INNATE_IMMUNE_CELL_Cytosol map
  6. IL13@default map


References
PMID:9535722
IL13 induces phosporylation of IRS2 and PLCG1 which is probably a PLC responsible for downstream IL13 dependent Ca2+??mobilization signaling and assosiation of IRS2 and PLCG1
PMID:7890616
PCL (probably PCLG1) induces t hydrolysis of phosphoinositides and activates InsP3-induced intracellular Ca2+??release downstream of IL13.