Complex CD74:MIF
Complex composition:
- CD74
- MIF
CD74:MIF@INNATE_IMMUNE_CELL_Membrane
Identifiers
NAME:CD74:MIF
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
Innate Immunity
/ IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS
References
CASCADE:MIF
DENDRITIC_CELL
PMID:12782713
MIF signal transduction initiated by binding to CD74.
CD74 Mediates MIF Induction of ERK-1/2 Phosphorylation, PGE2 Production, and Proliferation.
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
- CD74:MIF@INNATE_IMMUNE_CELL_Membrane
Participates in reactions:
As Reactant or Product:- MIF@default
+ CD74@INNATE_IMMUNE_CELL_Membrane
→
CD74:MIF@INNATE_IMMUNE_CELL_Membrane
As Catalyser:- ERK1/2*@INNATE_IMMUNE_CELL_Cytosol
→
ERK1/2*|pho@INNATE_IMMUNE_CELL_Cytosol
- PGE2@INNATE_IMMUNE_CELL_Cytosol
→
PGE2@default