Simple molecule ATP map
ATP@default

Maps_Modules
 Innate Immunity  map  / DANGER_SIGNAL_PATHWAYS  map

References
 DENDRITIC_CELL  map
 MACROPHAGE  map
CASCADE:STING
CASCADE::P2RX7
CASCADE::P2RY2
PMID:20086177
ATP was released by tumor cells succumbing to chemotherapy. ATP activates purinergic P2RX7 receptors on DC, thus activating the NLRP3/ASC/caspase-1 inflammasome and driving the secretion of interleukin-1beta (IL-1beta). IL-1beta then is required for the adequate polarization of IFNgamma-producing CD8(+) T cells.
PMID:19741708
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance.
UTP and ATP act via P2RY2 and promote P2Y(2)-dependent recruitment of phagocytes, and provide evidence for a clear relationship between a find-me signal and efficient corpse clearance in vivo.

ATP@INNATE_IMMUNE_CELL_Cytosol

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / DANGER_SIGNAL_PATHWAYS  map

References
 DENDRITIC_CELL  map
 MACROPHAGE  map
CASCADE:STING
CASCADE::P2RX7
CASCADE::P2RY2
PMID:20086177
ATP was released by tumor cells succumbing to chemotherapy. ATP activates purinergic P2RX7 receptors on DC, thus activating the NLRP3/ASC/caspase-1 inflammasome and driving the secretion of interleukin-1beta (IL-1beta). IL-1beta then is required for the adequate polarization of IFNgamma-producing CD8(+) T cells.
PMID:19741708
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance.
UTP and ATP act via P2RY2 and promote P2Y(2)-dependent recruitment of phagocytes, and provide evidence for a clear relationship between a find-me signal and efficient corpse clearance in vivo.
in_re1145( Innate Immunity  map ):
PMID:7890616
Intracellular Ca2+??release induces cAMP Accumulation in Human Monocytes and activation of PKA signaling downstream of IL13.


Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. ATP@INNATE_IMMUNE_CELL_Cytosol map
In compartment: default
  1. ATP@default map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. ATP:​P2RX7@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. ATP@INNATE_IMMUNE_CELL_Cytosol map map cAMP@INNATE_IMMUNE_CELL_Cytosol map
  2. ATP@INNATE_IMMUNE_CELL_Cytosol map map cGAMP@INNATE_IMMUNE_CELL_Cytosol map
  3. FIND_ME@TUMOR_CELL_AS_INDUCTOR map map ATP@default map
  4. ATP@default map + P2RX7@INNATE_IMMUNE_CELL_Membrane map map ATP:​P2RX7@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. P2RY2@INNATE_IMMUNE_CELL_Membrane map map P2RY2@INNATE_IMMUNE_CELL_Membrane map
  2. Caspase1*:​NLRP3:​PYCARD@INNATE_IMMUNE_CELL_Cytosol map map (NLRP3:​PYCARD:​cleaved Caspase1*)|​active@INNATE_IMMUNE_CELL_Cytosol map