Protein HSP70* map

Identifiers
heat shock 70kDa protein 1A
HUGO:HSPA1A
heat shock 70kDa protein 1B
HUGO:HSP1B
heat shock 70kDa protein 1-like
HUGO:HSPA1L
HUGO:HSPA1A HGNC:5232 ENTREZ:3303 UNIPROT:P08107
HUGO:HSPA1B HGNC:5233 ENTREZ:3304 UNIPROT:P08107
HUGO:HSPA1L HGNC:5234 ENTREZ:3305 UNIPROT:P34931
"heat shock 70kD protein 1A", HSPA1
HUGO:HSPA1A HGNC:5232 ENTREZ:3303 UNIPROT:P08107 GENECARDS:HSPA1A REACTOME:56682 KEGG:3303 ATLASONC:GC_HSPA1A WIKI:HSPA1A HUGO:HSPA1B HGNC:5233 ENTREZ:3304 UNIPROT:P08107 GENECARDS:HSPA1B REACTOME:56682 KEGG:3304 ATLASONC:GC_HSPA1B WIKI:HSPA1B

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / RCD_GENES  map
 Regulated Cell Death  map  / ER_STRESS  map
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_NON_CANONICAL  map

References
PMID:20959453
PMID:23430059
CASCADE:TLR2_4
PMID:25103413
Hypoxia downregulates HSP70 level in membrane.
PMID:20093776
Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells via TLR2/MyD88 dependent IL6 expression.

Modifications:
In compartment: TUMOR_CELL_AS_INDUCTOR
  1. HSP70*@TUMOR_CELL_AS_INDUCTOR map
In compartment: default
  1. HSP70*@default map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. HSP70*@TUMOR_CELL_AS_INDUCTOR map → map HSP70*@default map
    As Catalyser:
    1. TLR2/4*@INNATE_IMMUNE_CELL_Membrane map + LY96@INNATE_IMMUNE_CELL_Membrane map + TIRAP@INNATE_IMMUNE_CELL_Membrane map + MYD88@INNATE_IMMUNE_CELL_Membrane map + CD14@INNATE_IMMUNE_CELL_Membrane map → map CD14:​LY96:​MYD88:​TIRAP:​TLR2/4*@INNATE_IMMUNE_CELL_Membrane map