Complex ACTR2:ACTR3:ARPC1*:ARPC2:ARPC3:ARPC4:ARPC5:WASP* map
Complex composition:

  1. ACTR2 map
  2. ARPC5 map
  3. ACTR3 map
  4. ARPC2 map
  5. ARPC1* map
  6. ARPC4 map
  7. ARPC3 map
  8. WASP* map

ACTR2:​ACTR3:​ARPC1*:​ARPC2:​ARPC3:​ARPC4:​ARPC5:​WASP*|​pho@INNATE_IMMUNE_CELL_Cytosol

Identifiers
NAME:ACTR2:ACTR3:ARPC1*:ARPC2:ARPC3:ARPC4:ARPC5:WASP*

References
 MACROPHAGE  map
 NATURAL_KILLER  map
CASCADE:CR3
CASCADE:Fc_gamma_RII
PMID:11395419
Arp2/3 complex is intrinsically inactive, relying on nucleation promoting factors for activation. WASp/Scar family proteins are prominent cellular nucleation promoting factors. They bring together an actin monomer and Arp2/3 complex in solution or on the side of an existing actin filament to initiate a new filament that grows in the barbed end direction.
PMID:10783245; PMID:12194823
Arp2/3 complex regulates phagocytosis mediated by Fc??R (Fc_gamma_RII) or CR3.

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. ACTR2:​ACTR3:​ARPC1*:​ARPC2:​ARPC3:​ARPC4:​ARPC5:​WASP*|​pho@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. ACTR2:​ACTR3:​ARPC1*:​ARPC2:​ARPC3:​ARPC4:​ARPC5@INNATE_IMMUNE_CELL_Cytosol map + WASP*|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map → map ACTR2:​ACTR3:​ARPC1*:​ARPC2:​ARPC3:​ARPC4:​ARPC5:​WASP*|​pho@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. Actin cytoskeletal*@INNATE_IMMUNE_CELL_Cytosol map → map Actin cytoskeletal*|​hm2|​active@INNATE_IMMUNE_CELL_Cytosol map