Protein ARL14 map

Identifiers
HUGO:ARL14

References
 DENDRITIC_CELL  map
PMID:21458045
MHC-II transport was controlled by the GTPase ARL14/ARF7, which recruits the motor myosin 1E via an EFFECTOR_ACTIVATION protein ARF7EP. This complex controls movement of MHC-II vesicles along the actin cytoskeleton in human dendritic cells (DCs).

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. ARL14:​GDP@INNATE_IMMUNE_CELL_Cytosol map
  2. ARL14:​GTP@INNATE_IMMUNE_CELL_Cytosol map
  3. ARL14:​ARL14EP:​GTP:​MYO1E@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. ARL14:​GDP@INNATE_IMMUNE_CELL_Cytosol map + GTP@INNATE_IMMUNE_CELL_Cytosol map → map ARL14:​GTP@INNATE_IMMUNE_CELL_Cytosol map + GDP@INNATE_IMMUNE_CELL_Cytosol map
  2. ARL14:​GTP@INNATE_IMMUNE_CELL_Cytosol map + ARL14EP@INNATE_IMMUNE_CELL_Cytosol map + MYO1E@INNATE_IMMUNE_CELL_Cytosol map → map ARL14:​ARL14EP:​GTP:​MYO1E@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. MHC_class_II*:​Tumor_antigen_fragment@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map → map MHC_class_II*:​Tumor_antigen_fragment@INNATE_IMMUNE_CELL_Membrane map