Reaction transport in_re28 map

MHC_class_II*:​Tumor_antigen_fragment@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map → MHC_class_II*:​Tumor_antigen_fragment@INNATE_IMMUNE_CELL_Membrane map

Reaction regulators:
Catalysis
  1. GTP:​RHOB@INNATE_IMMUNE_CELL_Cytosol map
  2. ORP1L*:​RAB7*:​RILP@INNATE_IMMUNE_CELL_Cytosol map
  3. ARL14:​ARL14EP:​GTP:​MYO1E@INNATE_IMMUNE_CELL_Cytosol map
  4. Actin polymerization@INNATE_IMMUNE_CELL_Cytosol map


References
PMID:21458045
MHC-II transport was controlled by the GTPase ARL14/ARF7, which recruits the motor myosin 1E via an EFFECTOR_ACTIVATION protein ARF7EP. This complex controls movement of MHC-II vesicles along the actin cytoskeleton in human dendritic cells (DCs).